I've been playing this game a lot and with all bugs I've seen and places I got stuck in - none of that ruined hours of my hard and tedious work. This game saves every progress you do, only your position is saved on "checkpoints". So If something "bad" happens to your game you will be needed to travel back few meters to continue on from the place you left.
Greetings,
You might want to check one elevator in particular then, after the main headquarter, located near the location of a female doctor that you can save after meeting her dying boyfriend. If you take that elevator down, you'll face a long tunnel with some bright light at the end. As soon as I step approximately ten steps or so inside, my whole screen turns black. The U.I. remains visible, I can still see the four azure dots on the protagonist's arm, and nothing else whatsoever.
I assume that I can still move her since I can hear footsteps, I can also hear enemies but I don't see anything. Trying to go back to the elevator doesn't fix the issue. Reloading the save file doesn't fix the issue either. Quitting the video-game entirely and re-starting doesn't work. So any progress achieved up to that point is effectively lost.
I also encountered a bug once, which got me stuck inside a building's door. All the aforementioned applied as well : reloading or re-starting the video-game didn't help, hours of hard work lost in a matter of seconds. I've come to dread any moving object and piece of geometry in that video-game, thus why I've resorted to Unreal Engine Unlocker to acquire DevConsole and NoClip out of spaces that get me stuck.
Nothing worked for the black screen issue, which seemed to occur one hundred percent in that underground tunnel, and sometimes in some abandoned houses (but that seemed completely random). I also had an issue that caused my character to become unable to reload her firearms, the R button no longer worked even if all the magazines were fully loaded in her inventory. I'll add a note about the stress-related items (cigarettes, antidepressant...) being consumed but not performing their intended effect nearly half of the time.